产品货号：
Z16150
中文名称：
FOXL2抗体
英文名称：
Anti-FOXL2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FOXL2 Antibody |
| 指标别名 | BPES;BPES1;forkhead box L2;Forkhead box protein L2;FOXL2;FOXL2-Specific;PFRK;PINTO;POF3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | FOXL2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human FOXL2 (ACARQPELAMMHCSYWDHD). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The forkhead transcription factor gene,FOXL2 located in blepharophimosis-ptosis-epicanthus inversus syndrome(BPES) critical region on chromosome 3q23.Consistent with an involvement in BPES,FOXL2 is selectively expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles;in adult humans,it appears predominantly in the ovary.FOXL2 haploinsufficiency may cause BPES types I and II by the effect of a null allele and a hypomorphic allele,respectively.Furthermore,in a fraction of the BPES patients the genetic defect does not reside within the coding region of the FOXL2 gene and may be caused by a position effect.FOXL2 mutations can also cause gonadal dysgenesis or premature ovarian failure(POF) in women,as well as eyelid/forehead dysmorphology in both sexes. |
| Uniprot ID | P58012 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | forkhead box L2 |
| 蛋白名全称 | Forkhead box protein L2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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